 Movie generated with PyMOL |
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A: g.3.11.1 (red/blue) 
B: b.2.1.1 (yellow) 
C: c.10.2.5 (green) 
Geometric Parameters
| RMSD A1-A2 | 1.03 |
| Shared interface atoms | 378 (77.5%) |
| Angle between green and yellow interface: | 7.80 |
| Angle between green and yellow domain: | 33.71 |
| Distance between center of mass of green and yellow interface (in Angstrom): | 5.19 |
| Distance between center of mass of green and yellow domain (in Angstrom) | 12.07 |
Sequence Alignment of domain g.3.11.1
pclrkYkdFcih-gecKYVKELRAPSCICHPGY-HGERCh-----glS ecplshdgyclhdgvcMyIeALdKyACNCVVgYI-GERcqyrDlkWwe _ _ ._:_.#_._:#.#.._# ###_ _ _ | |
Aligned interface residues . : # | 15 (60%) |
Aligned, similar interface residues (with positive BLOSUM value) : # | 9 (36%) |
| Raw BLOSUM-Score for the latter residues | 49 |
| Meaning | |
|---|---|
Capital letters |
Residue interacts with domain A |
# |
Identical interacting residues |
: |
Residues are similar and interact |
. |
Residues are not similar and interact |
_ |
Only one residue interacts |
Sequences of domain b.2.1.1 and c.10.2.5
SPgHktqpFlHDgyavswntvedsiirtgfqgesghdikitaentplpiAgvLlPtipgkldvnkskthisvngrkirmR cRaIDgDVtFcRpkspvyvgngvhanlhvafhrsssekihsneISSDSigvLgyQKtVDhTKVNSKlSlFfeiks ekkvcqgTsNKLTQLGTfeDhflSlqRmfnncevvlgnleitYvqrnydlsflktiqevagyvliALntveriplenlqi irgnmyYEnsyalavLSnYdanktglkelpmrnlqeilhgavrfsNnpalcnvesiqwrdivssdflsnmsmdfqnhlgs |
Similarities between domain b.2.1.1 and c.10.2.5
| Residue Pair | Atom Matches | BLOSUM | Score | Avg.-Distance |
|---|---|---|---|---|
| Asp507-Asp22 | 
 |
6 | 6.52 | 2.48 |
| Arg460-Tyr101 | 
|
-2 | 5.97 | 1.37 |
| Lys526-Lys13 |
|
5 | 5.89 | 1.66 |
| Lys516-Lys13 |
|
5 | 5.91 | 1.64 |
| Ala430-Ala68 |
|
4 | 4.64 | 2.36 |
| Leu512-Leu14 | |
4 | 4.34 | 1.98 |
| Gln515-Glu90 |
|
2 | 4.41 | 1.97 |
| Arg472-Ser99 |
|
-1 | 2.71 | 1.64 |
| Phe389-Thr10 |
|
-2 | 2.48 | 1.76 |
| Ser508-Leu17 |
|
-2 | 2.45 | 1.78 |
| Asn524-Leu14 |
|
-3 | 2.27 | 1.30 |
| Lys526-Thr15 |
|
-1 | 2.21 | 1.67 |
| Ser525-Lys13 |
|
0 | 2.07 | 1.97 |
| Lys526-Asn12 |
|
0 | 1.86 | 1.61 |
| Ala430-Leu98 |
|
-1 | 1.47 | 1.53 |
| Arg472-Tyr101 |
|
-2 | 1.42 | 1.58 |
| Asn524-Lys13 |
|
0 | 1.28 | 1.72 |
| His384-Arg29 |
|
0 | 1.22 | 2.27 |
| Ser506-Thr19 |
|
1 | 1.28 | 2.58 |
| Phe530-Ser26 |
|
-2 | 1.29 | 2.23 |
| Phe470-Leu69 |
|
0 | 1.27 | 1.10 |
| Leu433-Tyr45 |
|
-1 | 1.06 | 1.94 |
| Ser528-Leu17 |
|
-2 | 1.08 | 1.39 |
| His391-Thr10 |
|
-2 | 0.95 | 2.29 |
| Arg472-Asn128 | |
0 | 0.46 | 1.63 |
| Ser506-Asp22 | |
0 | 0.45 | 1.66 |
| Pro435-Thr19 |
|
-1 | 0.46 | 2.54 |
| Pro435-Gly18 | |
-2 | 0.49 | 1.54 |
| Asn524-Tyr89 | |
-2 | 0.48 | 1.56 |
| Phe530-Arg29 | |
-3 | 0.35 | 1.95 |
| Leu433-Gln16 | |
-2 | 0.10 | 2.69 |
| Ser506-Gly18 | |
0 | 0.16 | 2.53 |
| Leu512-Ala68 | |
-1 | 0.01 | 2.98 |
| Total Score | 68.96 | |||
| | ||||
| Symbol | Atom match between | |||
| C-alpha atoms within 3 A | |||
| C-beta atoms within 3 A | |||
| backbone atoms within 3 A | |||
| side chain atoms within 2 A | |||
|
The score for each residue pair is simply its BLOSUM score (if positive) + the sum of atom pair scores. The latter are between 0 and 1, with 0 for 3A distance or above and 1 for exact coordinate matches, linearly interpolated. | ||||
